Bernardo Almeida

Bernardo Almeida

AI Senior Research Scientist at InstaDeep

"The people who are crazy enough to think they can change the world are the ones who do!"

Steve Jobs

About

Bernardo Almeida

Bernardo Almeida

AI Senior Research Scientist at InstaDeep

I am an AI Senior Research Scientist at InstaDeep, where I am building large language foundational models for biology. My work focuses mostly on developing deep learning models that can read the human genome and interpret its variation.

My broader research interests include Deep Learning, Genomics and Personalized Medicine. I previously completed my PhD at the Research Institute of Molecular Pathology (IMP) in Vienna, working with Alex Stark on using deep learning and massively parallel reporter assays to decode the regulatory grammar of regulatory DNA sequences.
AI Research Genomics Deep Learning Gene Regulation
Learn more about me

News

2025-12
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We are excited to introduce Nucleotide Transformer v3 (NTv3) - InstaDeep's new foundation model for long-range multi-species genomics 🎉

Preprint, HuggingFace Space, Twitter thread

2024-09

Our work on the "Nucleotide Transformer: building and evaluating robust foundation models for genomics" was presented at CSHL Systems Biology (March 2024) and MLCB (September 2024) conferences

2024-05
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Very happy to receive 2024 Denise P. Barlow Award for best PhD thesis on biological mechanisms in Vienna, Austria (May 2024)

For more information see here

2023-12
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It was great to participate in the podcast Futuro do Futuro (in portuguese) and discuss my work and the future of AI in biology (December 2023)

2023-12

My final PhD paper on designing synthetic enhancers for selected tissues in vivo using AI is out in Nature (December 2023)

2023-11

I am very happy to have received one of the 2023 Vienna BioCenter PhD Awards! Shared with great colleagues. It's the best way to close the PhD at the IMP, in Vienna (November 2023)

Research highlights

Featured Research
DeepSTARR predicts enhancer activity from DNA sequence and enables the <em>de novo</em> design of synthetic enhancers

DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers

Nature Genetics 2022

New publication where we use deep learning to predict enhancer activity from DNA sequence, learn cis-regulatory rules and the importance of TF motif instances, and design synthetic enhancers.

Featured commentary: Lin Tang. "Predicting and designing enhancers". Nature Methods 2022

Awarded the Life Science Research Award Austria 2022, by ÖGMBT

Harnessing artificial intelligence to predict and control gene regulation